Klasemen Serie A Italia Musim 2020-2021 menunjukkan rekor setiap tim di turnamen sepanjang musim yang akan selalu diupdate setiap saat setelah pertandingan berakhir.
| # | Team | MP | W | D | L | F | A | G | P |
|---|---|---|---|---|---|---|---|---|---|
| 1 | SSC Napoli | 7 | 5 | 2 | 0 | 15 | 5 | +10 | 17 |
| 2 | Atalanta | 7 | 5 | 2 | 0 | 11 | 3 | +8 | 17 |
| 3 | Udinese | 7 | 5 | 1 | 1 | 15 | 7 | +8 | 16 |
| 4 | Lazio | 7 | 4 | 2 | 1 | 13 | 5 | +8 | 14 |
| 5 | AC Milan | 7 | 4 | 2 | 1 | 13 | 8 | +5 | 14 |
| 6 | Roma | 7 | 4 | 1 | 2 | 8 | 7 | +1 | 13 |
| 7 | Inter Milan | 7 | 4 | 0 | 3 | 13 | 11 | +2 | 12 |
| 8 | Juventus | 7 | 2 | 4 | 1 | 9 | 5 | +4 | 10 |
| 9 | Torino | 7 | 3 | 1 | 3 | 6 | 7 | -1 | 10 |
| 10 | Fiorentina | 7 | 2 | 3 | 2 | 7 | 6 | +1 | 9 |
| 11 | Sassuolo | 7 | 2 | 3 | 2 | 5 | 8 | -3 | 9 |
| 12 | Spezia | 7 | 2 | 2 | 3 | 7 | 11 | -4 | 8 |
| 13 | Salernitana | 7 | 1 | 4 | 2 | 10 | 8 | +2 | 7 |
| 14 | Empoli | 7 | 1 | 4 | 2 | 6 | 7 | -1 | 7 |
| 15 | Lecce | 7 | 1 | 3 | 3 | 6 | 8 | -2 | 6 |
| 16 | Bologna | 7 | 1 | 3 | 3 | 7 | 10 | -3 | 6 |
| 17 | Verona | 7 | 1 | 2 | 4 | 6 | 13 | -7 | 5 |
| 18 | Monza | 7 | 1 | 1 | 5 | 4 | 14 | -10 | 4 |
| 19 | Cremonese | 7 | 0 | 2 | 5 | 5 | 14 | -9 | 2 |
| 20 | Sampdoria | 7 | 0 | 2 | 5 | 4 | 13 | -9 | 2 |
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